La Putrescina, Spermina e Spermidina contenute negli alimenti

La Putrescina, Spermina e Spermidina contenute negli alimenti
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Le poliammine sono sostanze dall’odore fetido, presenti in tutti gli alimenti, nei microorganismi, nelle piante, nei funghi e nelle cellule umane;

La presenza di poliammine nell’organismo deriva da tre fonti:

  1. dalle cellule dell’organismo in proliferazione, che lo producono e lo riversano nel sangue
  2. Dalla flora microbica intestinale, in particolare dai batteri cattivi tipici di chi mangia poca frutta, verdura e cibi integrali e mangia molti prodotti carnei, fermentati e formaggi.
  3. Dall’assunzione di alcuni alimenti particolarmente ricchi di poliammine come le Arance, i pompelmi, il Mango, i madarini, i formaggi e le carni

Le poliammine, svolgono importanti funzioni nell’organismo, quali:

  1. favoriscono la proliferazione e crescita cellulare
  2. proteggono il DNA dai radicali liberi
  3. Fungono da agenti antiossidanti
  4. prevengono la formazione di proteine glicate, quindi utili nei diabetici.
  5. Sono sostanze immunosoppressori, quindi da una parte riducono le forme allergiche, e dall’altra indeboliscono il sistema immunitario.

Tuttavia, nei malati oncologici, la produzione di poliammine nel sangue, tende ad incrementare;

Infatti i malati di tumore, presentano alti livelli di putrescina, spermina e spermidina nel sangue e nelle urine;

Si è anche notato che i malati di tumore che si sottopongono a intervento chirurgico per rimuovere la massa tumorale, vedono nei giorni successivi scendere i livelli di Poliammine sia nel sangue che nelle urine;

Molti autori, evidenziano come la quantità di poliammine nelle urine e nel sangue, siano correlati


all’aumento della proliferazione tumorale; più è invasivo e proliferativo il tumore, maggiore sarà la presenza di spermina, spermidina e putrescina nel sangue e urina.

Sembra che le cellule tuorali siano particolarmente ghiotti di Poliammine, in particolare di spermidina e spermina.

Poichè il tumore è caratterizzato da una notevole proliferazione e invasione cellulare, e poiché il tumore per attecchire, deve addormentare il sistema immunitario, ha necessità di produrre ed assorbire grandi quantità di putrescina, spermina, spermidina e cadaverina;

Le Poliammine “ad alte concentrazioni”, oltre a favorire la crescita e proliferazione tumorale, contribuisce ad indebolire il sistema immunitario, come le Natural killer.

Si è anche visto che nelle cellule Tumorali è fortemente espresso l’enzia Ornitina decarbossilasi, che favorisce la decarbossilazione dell’ornitina (un aminoacido) generando la Putrescina, la spermidina e la spermina.

Per queste ragioni, e per molte altre, molti oncologi suggeriscono ai loro pazienti, di ridurre il consumo di alimenti che apportano notevoli quantità di Poliammine;

Quindi, il consumatore, deve seguire una dieta ricca di frutta, verdura, legumi, cereali integrali accompagnate con moderate quantità di proteine animali; Una dieta ricca di fibra e cibi freschi, favorisce la crescita di una flora batterica intestinale amica, tale da ridurre la sintesi intestinale di poliammine.

Inoltre alcuni scienziati consigliano ai malati oncologici di ridurre certi cibi naturalmente ricchi di poliammine, come:

  1. L’arancia ed il succo di arancia (ricca di putrescina e spermidina)
  2. il mandarino (ricca di putrescina e spermidina)
  3. Il pompelmo ed il succo di pompelmo (ricca di putrescina e spermidina)
  4. il Mango (ricca di putrescina e spermidina)
  5. I formaggi (ricchissima in Spermidina, Spermina, Putrescina e cadaverina)
  6. I cibi fermentati orientali, come il Miso, etc.
  7. le carni fermentate COME GLI INSACCATI (ricche di Spermina e spermidina)
  8. Il Keciap (ricca di putrescina e spermidina)
  9. I Krauti (ricca di putrescina)
  10. La crusca di riso (ricca fonte di putrescina)

Fonti Bibliografiche

  1. I meccanismi attraverso i quali le poliammine accellerano la diffusione dei Tumori
  2. Le Poliammine negli alimenti: sviluppo di una banca dati alimentare (Svezia)
  3. Tabella contenuto delle poliammine negli Alimenti

Nota Legale 

Le Informazioni contenute in questo Blog non intendono sostituirsi al parere professionale del medico. L’utilizzo di qualsiasi informazione qui riportata è a descrizione del lettore. L’autore e l’amministratore del Blog si sottraggono a qualsiasi responsabilità diretta o indiretta derivante dall’uso o dall’applicazione da qualsivoglia indicazione riportata nel Blog Alimentazione e Nutraceutica. Per ogni problema specifico si raccomanda di consultare uno specialista

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Pubblicato da Dottor Liborio Quinto

Sono un appassionato di Biologia e Chimica degli Alimenti, e condivido con Voi, il Mio sapere. Chi è interessato a propormi qualcosa, può contattarmi

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